The constituency was originally created in 1984, following the division of the single constituency of Gaborone and has undergone multiple changes in its size and composition.

Gaborone South was a safe seat for the BNF between 1984 and 2009.

[2] It was the seat of Kenneth Koma, president of the BNF and leader of the Opposition between 1984 and 2003.

Molatlhegi was re-elected in 2014 and succeeded in 2019 by Dumezweni Mthimkhulu, also from the BDP.

The urban constituency encompasses the following locations:[3][4] Key: