[2] His sister, Henrietta Manigault, was the wife of Nathaniel Heyward, a wealthy rice planter who accumulated at least twenty-two plantations and assorted lands throughout the low country.

[1] His great-grandfather was Pierre Manigault (1664–1729), a French Huguenot who was born in La Rochelle, France and settled in Charleston.

[3] He went to study in Geneva and London, and came back to Charleston after the American Revolutionary War.

In 1805, Manigault sold part of his South Carolina land, and moved permanently to Clifton, an estate near Philadelphia, Pennsylvania.

Through his daughter Elizabeth, he was the grandfather of Margaret Ann "Meta" Morris (1810–1881), who married John Berkley Grimball;[1] and Capt.