Born in Moscow, Guseinov started playing chess under the guidance of Shahin Hajiev.

In 2008 tied for 1st–8th with Nigel Short, Vadim Milov, Aleksej Aleksandrov, Baadur Jobava, Alexander Lastin, Tamaz Gelashvili and Farid Abbasov in the President's Cup in Baku.

[3] In April 2010, Guseinov tied for 1st-8th place in the 12th Dubai Open Chess Championship with Viorel Iordachescu, Hrant Melkumyan, Sergey Volkov, Eduardo Iturrizaga, David Arutinian, Aleksej Aleksandrov and Tornike Sanikidze.

[6] Guseinov was nominated by FIDE president to compete in the Chess World Cup 2015 in Baku.

[7] He played in the gold medal-winning Azerbaijani team at the European Team Chess Championships in Novi Sad in 2009 and in Warsaw in 2013, alongside Shahriyar Mammadyarov, Teimour Radjabov, Vugar Gashimov (in 2009), Eltaj Safarli (in 2013) and Rauf Mammadov, previously winning bronze medal in 2007 and silver in 2011.