Galien (pronounced guh-LEEN)[4] is a village in Berrien County in the U.S. state of Michigan.

The village straddled a fairly new Michigan Central Railroad completed in 1849 from New Buffalo to Detroit.

Blakeslee operated a sawmill at the site of present-day Galien, and established a general store.

He purchased several thousand acres in the vicinity of the village and harvested the timber for his sawmill operation.

For many years after Galien was established, he was president of the village, postmaster, justice of the peace, member of the school board and later World Bishop of the Latter Day Saint's Church.

[6] Blakeslee Street was named after him and is located in the SE quadrant of the city plat.

On July 21, 1971, fire broke out in a hardware store in downtown Galien and destroyed that building as well as a restaurant and a beauty salon adjacent to it.

According to the United States Census Bureau, the village has a total area of 0.42 square miles (1.09 km2), all land.