Gamalakhe is situated north of the Vungu River, approximately 19 km (12 mi) from Port Shepstone and 15 km (9 mi) from Margate.

The nearest urban settlements are Uvongo, Shelly Beach, Margate and Port Shepstone.

Gamalakhe has a Community Health Centre, shopping centre, Post Office, Public Library, Social Development Offices, Civic Centre, Police Station and Public Swimming Pool.

Gamalakhe is mainly accessed by turning off the P200 Izotsha Road (to Izotsha and Ramsgate) onto the P482 which is the single access road into the township.

From the intersection with the P200, the P482 continues as the D202 towards St Michael’s-on-sea and Uvongo in the east.