Game Creek (Lingít: Xutshéeni[2]) is a census-designated place (CDP) on Chichagof Island in Hoonah-Angoon Census Area, Alaska, United States.

[4] It lies just southwest of the community of Whitestone Logging Camp and the city of Hoonah.

The CDP limits follow the shoreline of Port Frederick on the northwest as far south as Burnt Point.

Game Creek, the waterway, forms the eastern edge of the CDP as far north as its mouth in Port Frederick, and the southern limit extends from Burnt Point to Game Creek across an intervening 2,760-foot (840 m) summit.

[3] Game Creek first appeared on the 1990 U.S. Census as an unincorporated census-designated place (CDP).