Subsequently, he made his début in Tamil cinema with Radha Mohan's family drama, Abhiyum Naanum (2008).

During the period, Ganesh also opted out of another multi-starrer Mankatha (2011), and instead chose to work on another bilingual Tamil and Hindi film, Panithuli (2012), in a solo lead role.

The film opened to negative reviews and performed poorly at the box office.Then he played antagonist in Nagarjuna Starrer Damarukam.

[5] Ganesh subsequently worked on a few low budget films, the psychological thriller Achaaram (2015) and the drama Pallikoodam Pogamale (2015), both of which had limited theatrical releases.

[6] His following his releases have fared less well with Thodari (2016) and Nayaki (2016), where he portrayed the antagonist, earning negative reviews and performing poorly at the box office.