The episode deals with the gaslighting of Serena van der Woodsen (played by Blake Lively) as she copes with her supposed return to drug and alcohol abuse, the continued reluctance of Blair Waldorf (Leighton Meester) to resume a troubled relationship with her former flame, Chuck Bass (Ed Westwick), and short-lived return Jenny Humphrey (Taylor Momsen) to the Upper East Side as she and Vanessa Abrams (Jessica Szohr) face the consequences of working with Juliet Sharp (Katie Cassidy) in taking down Serena.

Blair remains firmly adamant against Serena for what she did to her and Chuck during his party from the previous episode and plans to leave New York to spend Thanksgiving in Paris with her father.

At the van der Woodsen apartment, Lily (Kelly Rutherford) releases her frustrations against Serena seemingly dropping out of college along with Eric (Connor Paolo).

Throughout the city, Dan and Vanessa discuss spending Thanksgiving together while Nate (Chace Crawford) incidentally receives his parents' divorce papers.

As Blair and Dorota arrive at the van der Woodsen apartment, she hands the pumpkin pie to Lily to honor her yearly traditions.

Meanwhile, a drugged and distressed Serena wakes up in a motel filled with pills and liquor bottles and calls 911 for help.

Vanessa, unaware that Serena is hospitalized, finds herself alone when she arrives at the van der Woodsen apartment and receives a text from Jenny implying that their plan to ruin had gone too far.

As Vanessa makes her way to the Ostroff Center to talk to Dan, she calls Juliet and expresses that they should tell the truth about what they did to Serena.

Juliet expresses her anger at losing her place and her life in Columbia in her attempt at trying to ruin Serena and leaves her brother.

Despite his efforts, Anne Archibald (Francie Swift) continues to move forward with her divorce from his father (Sam Robards) and disappoints Nate.

Long gone are the high schools days of the show's first two years, and here to stay seem to be adult consequences for the decisions the characters face."

"[5] Chris Rovzar and Jessica Pressler from New York Magazine however, considered the episode to be unrealistic and ridiculous but complimented Matthew Settle's performance and the minute interaction between Chuck and Blair.

Further praise went to Katie Cassidy's character, Juliet Sharp, with Steve Marsi declaring her "as one of the best villains in Gossip Girl history.

Berman praised the reduced interaction between Blair and Chuck as well as Vanessa's decline as a prominent character, citing her walking alone into Lily and Rufus' apartment to celebrate Thanksgiving only to find everyone gone but Dorota and her baby.