Gateway Center station was opened on July 3, 1985 as part of the new subway system that replaced the remaining downtown street running trolleys.

[1] Named for Gateway Center, the adjacent office complex, the station served the western portion of downtown.

Gateway Center closed on October 30, 2009, as part of the North Shore Connector project, and a newly constructed station (named Gateway) opened just north of the original station on March 25, 2012.

The original platform under Liberty Ave was left intact and abandoned, and can be seen while riding the train towards Wood Street.

Commissioned by Pittsburgh Regional Transit as part of the original station complex, the mural is now valued at $15 million.