[1][2][3] In addition to their LGBT advocacy, the GLN regularly campaigns with non-gay groups about issues concerning immigrant's and women's rights and the wars in Iraq and Afghanistan.

[8] Beginning in 2000, the organization frequently protested against the Chicago Police Department, for what they perceived as "anti-homosexual and racist attitudes", during arrests of LGBT citizens.

[12][13] In 2001, they supported, along with the ACLU, filing hate crime charges against a man who was verbally harassing gay Pakistani American poet Ifti Nasim in a Chicago restaurant.

[16] The GLN has been active in protesting against Jamaican singers Capleton and Buju Banton, who have received international criticism for their anti-gay lyrics that allegedly "promotes violence against gays and lesbians".

[17][18] In 2009, working alongside the Los Angeles LGBT Center, they were successful in convincing Live Nation to cancel its portion of a tour by Buju Banton, who had called for the "murder of gays in his songs".

[19] The GLN successfully lobbied the Southern Poverty Law Center to list the anti-gay organization Americans for Truth about Homosexuality as an anti-LGBT hate group in 2010.