[1][2] GeneTalk allows editing annotation about sequence variants and build up a crowd sourced database with clinically relevant information for diagnostics of genetic disorders.
Users can upload NGS data in Variant Call Format (VCF) onto the GeneTalk server into their accounts.
All entries of the file are preprocessed and shown in the integrated VCF viewer.
Filtering tools are set by the user to reduce the number of clinically non-relevant variants.
The communication platform allow users to contact experts about specific variants, genes, or genetic disorders, to exchange knowledge and expertise.