The General Secretariat of the Presidency of the Argentine Nation (Spanish: Secretaría General de la Presidencia de la Nación Argentina; SGP) is a secretariat of state of the Argentine National Executive counting with ministerial level, tasked with assisting the President of Argentina in the making of public policy, drafting messages and public speeches, maintaining the presidential protocol and overseeing the relationship between the President and society at large.

[2] The General Secretariat also oversees a number of centralized and decentralized agencies as defined by the Law on Ministries, which may be updated at the President's behest.

[5] The 1983 Law on Ministries (Spanish: Ley de Ministerios), decreed by Raúl Alfonsín, established eight secretariats reporting directly to the Office of the President tasked to delegate some of the President's direct responsibilities whilst aiding the head of state in the elaboration of public policies, among other responsibilities.

[7] The General Secretariat is entirely headquartered in the Casa Rosada, the official working residence of the President of Argentina.

In addition, the General Secretary also has responsibilities and jurisdiction over the Quinta de Olivos.