In order to form a better understanding, the instructions for making an entire set of DNA in a person or organism need be dissected, and the genes involved with this process need to be determined.
Due to the array of known enhancers, toxins and death genes are able to be attached to nearly any cell selected, which permits cell-type-specificity.
Through genetic ablation, the effects of removing every cell of a specific kind inside of an embryo are able to be observed; additionally, the entire population is able to be studied instead of just the individuals.
The numerous enhancers that exist allow this specificity because toxins and death genes are able to target essentially any cell of choice.
It is important to confirm that the toxin-encoding gene is only expressed during relevant developmental stages and in that specific cell in the embryo.
[4] Temporal control of gene expression and ablation can be attributed to evolving transgenic and gene-therapy technologies.
[5] Genetic ablation technology may be able to produce mice with mutations in just about every gene present in their germ line.
Although this technique is not perfected, it contains the ability to target questions surrounding the molecular and cellular biology of embryonic growth.
Furthermore, it may assist in the creation of animals to serve as guides showing the effects on human diseases including demyelination, dwarfism, and immunodeficiencies.