The station is owned by Rete Ferroviaria Italiana (RFI), a subsidiary of the Ferrovie dello Stato (FS) group.

The other entrances are in Piazza Nicolò Montano (interchange with numerous bus lines), Via Paolo Reti and Via Stefano Dondero.

Near the station are the termini of several lines of the local suburban public transport network, AMT (Genoa).

In the Via Paolo Rieti area, a few tens of meters (or yards) from the station, there is an AMT terminus served by buses showing Sampierdarena Rimessa on their destination boards.

Directly connected with the cargo port and the Genova Marittima Bacino railway station by a submarine tunnel, Sampierdarena Smistamento is composed of three separate yards: Sampierdarena Smistamento is also used as an exit for the Cargo Division locomotive depot located just to the north, in the district of Rivarolo.