Trained by Oskar Kokoschka in exile in London, Eisler soon developed his own artistic style.
Out of political reasons, his mother left Austria in 1936 and lived in with Georg for two years in Moscow.
In 1970, Otto Klemperer commissioned Eisler to design the sets and costumes for Mozart's The Magic Flute at Covent Garden Royal Opera House.
His work is in the permanent collections of the Albertina, the Portrait Gallery of the British Museum in London, the Bibliothèque Nationale in Paris and the Neue Nationalgalerie in Berlin.
In 2003, the Leica Company celebrated his lifelong friendship with Henri Cartier-Bresson by presenting a joint show of their work in Vienna.