George W. Blackburn [Smiling George] (September 21, 1869 – December 29, 1938) was an American right-handed pitcher in Major League Baseball who played for the Baltimore Orioles in the 1897 season.

A native of Ozark, Missouri, he spent 17 years in baseball as a player, coach, and manager Blackburn posted a 2–2 record with a 6.82 earned run average in five pitching appearances with the Orioles, allowing 30 runs (25 earned) on 34 hits and 12 walks while striking out one batter in 33 innings of work.

[1] On July 16, 1897, Cap Anson of the Chicago Cubs became the first player in major league history to reach 3,000 hits when he singled off Blackburn.

[3] Blackburn died in Oklahoma City on December 29, 1938, at the age of 69.

He donated his body to a medical school.