He was educated at James Monroe High School, New York University and Dartmouth College.
Carpozi was known as the "Biographer to the Stars," having written biographies on Brigitte Bardot, Marilyn Monroe – he conducted an extensive interview with Monroe, was one of the few biographers who knew her and was preparing a new edition of his biography at the time of his death, Clark Gable, Bobby Sherman, Vince Edwards, Jackie Kennedy, Gary Cooper, John Wayne, Frank Sinatra, John Lennon, Bing Crosby, Johnny Cash, Carol Burnett and Cher.
He was also the biographer of Kitty Kelley, Anwar Sadat, Andrew Young, Bugsy Siegel and Bill Clinton.
The Los Angeles Times said of him, "Carpozi is the archetypal police reporter, tough with a core of sentiment, knowledgeable about police procedure and courtroom strategy, intensely curious and always active ferreting out tips, watching the deadline for scoops, and not above eavesdropping if the opportunity presents itself ... Carpozi ... is closer to Damon Runyon than Tom Wolfe in his style".
Carpozi died at his home in Belle Terre, Long Island, New York of emphysema and heart failure.