George Chambers (February 24, 1786 – March 25, 1866) was an Anti-Masonic member of the U.S. House of Representatives from Pennsylvania.
He graduated from Princeton College in 1804, studied law, was admitted to the bar in 1807 and commenced practice in Chambersburg.
After his time in Congress, he resumed the practice of law and was a member of the State constitutional convention in 1837.
He was appointed a justice of the Pennsylvania Supreme Court on April 12, 1851, which position he held until it was vacated by constitutional provision.
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