George Earle Chamberlain Sr. (January 1, 1854 – July 9, 1928) was an American attorney, politician, and public official in Oregon.

[1] Dr. Chamberlain quickly built a large and prosperous practice, which enabled him to maintain his Maryland-born wife, the former Pamelia H. Archer, and family in comfort.

[1] George Earle Chamberlain attended public schools in Natchez, completing his secondary education in 1870 at the age of 16.

Following graduation from Washington and Lee, Chamberlain briefly returned home to Natchez but decided that professional prospects in the post-bellum South were marginal at best and he departed for a new life in Oregon, arriving on December 6, 1876.

A member of the Democratic Party, Chamberlain ran for the Oregon House of Representatives in November 1880, winning election to a two-year term.

He was a member of the United States Shipping Board from 1921 to 1923 and engaged in the practice of law in Washington, D.C. Chamberlain married his longtime personal secretary, Carolyn B. Shelton, on July 12, 1926, in Norfolk, Virginia.

[4] During his life Chamberlain was a member of the Independent Order of Odd Fellows, Knights of Pythias, and was a 32nd degree Mason in Portland.