George Hosmer (30 August 1781 in Farmington, Connecticut – 6 March 1861 in Chicago, Illinois) was a U.S. lawyer and politician.
He was a son of surgeon Timothy Hosmer (born in Middletown, Connecticut, in 1740; died in Canandaigua, New York, in 1820).
Timothy was a brother of Connecticut politician Titus Hosmer, and an officer in the Continental Army, serving throughout the American Revolutionary War, for two years and a half surgeon on Washington's staff.
George Hosmer received a classical education, studied law, and, after practising a year in Canandaigua, moved to Avon, New York.
A member of the New York State Legislature in 1823-1825, he declined renomination, and resumed his legal practice.