He led excavations in many prehistoric settlements in Thessaly and Macedonia (such as Dimini, Arkadikos Dramas etc.)
and in 1992 he started the excavation of the neolithic lakeside settlement of Dispilio in Kastoria, Northwestern Greece.
A myriad of items were discovered, which included ceramics, structural elements, seeds, bones, figurines, personal ornaments, three flutes (considered the oldest in Europe) and the Dispilio Tablet.
The site's paleoenvironment, botany, fishing techniques, tools and ceramics were published informally in the June 2000 issue of Επτάκυκλος, a Greek archaeology magazine and in Hourmouziadis (2002).
In 2012, he was part of a multidisciplinary team of scientists who published a result on the use of Mass spectrometry (C13/C12 Carbon and O18/O16 oxygen) and cathodoluminescence microscopy for tracing back the physical origin of spondylus shell artifacts to reconstruct ancient trade and exchange routes.