George Kirke Spoor (December 18, 1871 – 24 November 1953) was an early film pioneer who, with Gilbert M. "Broncho Billy" Anderson, founded Essanay Studios in Chicago in 1907.

[1] Spoor and Anderson were responsible for discovering stars such as Wallace Beery, Francis X. Bushman, Ben Turpin, Gloria Swanson and Charlie Chaplin.

In 1894, while box office manager of the Phoenix Opera House in Waukegan, Illinois, George K. Spoor teamed up with the inventor Edward Hill Amet (1860–1948) to build and exhibit "The Magniscope", the first practical 35 mm movie projector ever designed and used in a large audience display.

Spoor is also remembered for having produced, in 1918, the movie Men Who Have Made Love to Me by controversial feminist Mary MacLane, the first serious cinematic work to break the fourth wall.

In 1926, Spoor and P. John Berggren invented "Natural Vision", an early 65 mm widescreen process which was only used for a few films, including Niagara Falls (1926), Rollercoaster Ride (1926), The American (1927) and Danger Lights (RKO Radio Pictures, 1930).