George Lorin Miller (c. 1830 – 1920) was an American pioneer physician, editor, politician, and land owner in Omaha, Nebraska.

In 1855 Miller requested that the Congregationalist Church send a minister to Omaha, leading to the assignment of Reuben Gaylord, the city's foremost Christian missionary in its early years.

Miller helped recruit the First Nebraska Regiment prior to the Civil War and served as sutler at Fort Kearny until 1864.

Miller was attacked by Republican Edward Rosewater of the Omaha Bee on September 6, 1876, as a "jack-of-all trades and a master of none.

a medicine man, a hotel builder, an army sutler, a cotton speculator, a railroad jobber, an eating-house keeper, journalist, and a politician.

In the 1870s he helped Omaha land placement along the First transcontinental railroad and the Union Pacific Missouri River Bridge.

Miller helped the new St. Martin of Tours Episcopal Church acquire the limestone used in the mansion, and that building still stands.

Sterling Morton, the other prominent member of the Democratic Party in Nebraska, was a bitter enemy of Miller's during this period.