Born at Halesworth in Suffolk on 16 February 1772, he was the only son of John Tuthill, an attorney there, by his wife Sarah, only daughter of James Jermyn of the same town.
He received his education at Bungay under Mr. Reeve, and on 3 June 1790 was admitted sizar at Caius College, Cambridge.
He was nominated to give the Harveian oration on 25 June 1835, but died first; that year, with Sir Henry Halford and William George Maton, he helped reform the Royal College of Physicians.
[3] Tuthill died at his house in Cavendish Square, London on 7 April 1835, and was buried at St. Albans on the 14th of the same month.
[2] Tuthill was a member of the committee for the preparation of the Pharmacopœia Londinensis of 1824, and was responsible for the language of the work itself.
He left an only daughter, Laura Maria, married to Thomas Borrett, a solicitor in London.