Born on 4 January 1773 at Quainton, Buckinghamshire, he was the son of James Lipscomb, surgeon R.N., by Mary, daughter of Jonathan George, yeoman, of Grendon Underwood in the same county.
After attending schools at Quainton and Aylesbury, and receiving some medical instruction from his father, he studied surgery in London under Sir James Earle.
[2][3] Lipscomb's major work, The History and Antiquities of the County of Buckingham, was mainly based upon his own collections and those bequeathed to him by Edward Cooke (1772–1824).
Ultimately the publisher John Bowyer Nichols came to his aid, and before he died the last portion (pt.
His other topographical works were:[1][4] His medical writings were:[1] Other works included:[1] Articles by Lipscomb appeared in the Gentleman's Magazine, mainly under the signature of "Viator"; and his essays on subjects connected with political economy, statistics, and general literature were published in the Literary Panorama and other periodicals.
[1] Lipscomb married, in 1803, Sarah, the widow of Richard Hopkins of Stratford-upon-Avon, Warwickshire, and third daughter of Thomas Wells, also of Stratford.