George May Keim (March 23, 1805 – June 10, 1861) was a 19th-century American lawyer and politician who for three terms was a Democratic member of the U.S. House of Representatives from Pennsylvania from 1838 to 1843.

He attended Princeton College, studied law, was admitted to the bar in 1826 and commenced practice in Reading.

Keim was elected as a Democrat to the Twenty-fifth Congress to fill the vacancy caused by the resignation of Henry A. P. Muhlenberg.

He was the chairman of the United States House Committee on Militia during the Twenty-sixth and Twenty-seventh Congresses.

He was mayor of Reading in 1852, and was a presidential elector on the Democratic ticket of Stephen A. Douglas and Herschel V. Johnson in 1860.