George Washington Payne (May 23, 1889 – January 24, 1959) was a Major League Baseball pitcher.

Payne had a long career in the minor leagues, spanning twenty-eight years.

His professional career began in 1913, when he appeared in one game for the Charleston Sea Gulls of the South Atlantic League.

His final year came in 1940, when he managed and pitched in nine games for the Worthington Cardinals of the class-D Western League at the age of 51.

He pitched in the Texas League for the Wichita Falls Spudders (1927–1929) and Houston Buffaloes (1930–1934).