Seremetis was born in 1879 in Skamnia Elassonas, then ruled by the Ottoman Empire.
Shortly after his birth, the city of Larissa was liberated and his family moved there.
In 1897, George Seremetis started his studies at a law school of the University of Athens.
From 1926 to 1945, he was elected president of the Thessaloniki bar association by a large majority.
He later succeeded with the help of D. Vlachos to establish a "Lawyers' Fund of Welfare" (Greek: Tαμείο Προνοίας Νομικών) in Thessaloniki.