George Smith (1749–1823) was the minister at Galston, East Ayrshire, from 1778 until his death.

Galston is a village in Ayrshire a few miles north of Burns's farm at Mossgiel.

Burns had been reproved by Dr Smith, and Burns retaliated by pillorying Smith twice, by name, in "The Holy Fair", where he says that "his English tongue and gesture fine are a' clean oot o' season".

He is buried in Galston Parish Church (which was built during his ministry, opened on 18 June 1809).

Their son Rev George Smith DD (1793–1866) was minister of the Tolbooth parish in Edinburgh.