George Worthington (businessman)

On November 16, 1840, Worthington married Maria Cushman Blackmar, and soon after, moved into his newly constructed home on Euclid Avenue, the street which would, in the second half of the 19th century, come to be known as Millionaire's Row.

Maria C. Worthington had eight children; five girls and three boys, one of each dying in infancy, leaving his two sons, Ralph and his younger brother, George Jr., to inherit their father's business interests upon his death in 1871.

Afterwards, he purchased the stock of Cleveland, Sterling & Co., on the corner of Water and Superior streets, where the National Bank buildings now stand, and associated with himself as business partner of Mr. William Bingham.

In 1865, Worthington was among the Cleveland businessmen who organized the Hahnemann Life Insurance Company (named for German physician Samuel Hahnemann), the first such firm in the U.S. to offer to insure those whose medical belief and practice were exclusively homeopathic, at lower rates than those subjecting themselves to traditional medical treatment; as some contemporary evidence showed a lower rate of mortality under the former.

Designed by the Cleveland architectural firm of Cuddell and Richardson, The George Worthington Building is noted as a "highly decorative brick structure, notable for its unusually wide window bays grouped in two multi-story arched ranks, a brick cornice, recessed spandrels and finials."