The founder Academicians of the Academy were Giorgi Akhvlediani (linguistics), Ivane Beritashvili (physiology), Arnold Chikobava (Ibero-Caucasian languages), Giorgi Chubinashvili (arts), Simon Janashia (history), Alexander Janelidze (geology), Korneli Kekelidze (philology), Niko Ketskhoveli (botany), Tarasi Kvaratskhelia (subtropical cultures), Niko Muskhelishvili (mathematics, mechanics; first President of the Academy), Ilia Vekua (mathematics; second President of the Academy), Akaki Shanidze (linguistics), Alexander Tvalchrelidze (mineralogy), Dimitri Uznadze (psychology), Kiriak Zavriev (constructive mechanics) and Philip Zaitsev (zoology).
), George Nakhutsrishvili (botany), Vladimer Papava (economics), David Lordkipanidze (palaeoanthropology), etc.
[2] Presidents of the Georgian National Academy of Sciences: Niko Muskhelishvili (1941–1972), Ilia Vekua (1972–1977), Evgeni Kharadze (1977–1986), Albert Tavkhelidze (1986–2005), Tamaz V. Gamkrelidze (2005–2013), Giorgi Kvesitadze (2013-2023), and Roin Metreveli (2023- ).
Georgian scientific schools of mathematics, physics, psychology, philosophy, physiology, botany, oriental studies, linguistics, history, archaeology, ethnography and paleobiology have won world recognition.
GNAS is a National Scientific Associate of the International Council for Science (ICSU, France).