They had three children:[1] The earl already had an illegitimate daughter, Harriet, born around 1790 to his mistress, Madame Saint-Albin.

[3] Through the marriage between the earl and Georgina Bertie, the ancient hereditary office of Lord Great Chamberlain (which had been held by her brother, Robert Bertie, 4th Duke of Ancaster and Kesteven, until his death in 1779) passed into the Cholmondeley family.

Their family home was Cholmondeley Castle in Cheshire, which was rebuilt in 1801-04 according to the earl's own design.

Lord Cholmondeley, who was fifteen years his wife's senior, died in 1827, and was succeeded by his eldest son George.

The dowager marchioness died at Carlton House Terrace in London, aged 73.