German submarine U-1001 was a Type VIIC/41 U-boat of Nazi Germany's Kriegsmarine during World War II.

She was ordered on 14 October 1941, and was laid down on 31 December 1942, at Blohm & Voss, Hamburg, as yard number 201.

The submarine was powered by two Germaniawerft F46 four-stroke, six-cylinder supercharged diesel engines producing a total of 2,800 to 3,200 metric horsepower (2,060 to 2,350 kW; 2,760 to 3,160 shp) for use while surfaced, two BBC GG UB 720/8 double-acting electric motors producing a total of 750 metric horsepower (550 kW; 740 shp) for use while submerged.

The next day, 22 Sep 1944, U-1001 rescued 13 shipwrecked German soldiers from the Baltic and landed them later on 2 October, at Libau.

U-1001 was sunk by depth charges in the North Atlantic south-west of Land's End, killing all forty-six of her crew.