German submarine U-1272 was a Type VIIC/41 U-boat of Nazi Germany's Kriegsmarine during World War II.

She was ordered on 23 March 1942, and was laid down on 31 May 1943, at Bremer Vulkan-Vegesacker Werft, Bremen-Vegesack, as yard number 67.

The submarine was powered by two Germaniawerft F46 four-stroke, six-cylinder supercharged diesel engines producing a total of 2,800 to 3,200 metric horsepower (2,060 to 2,350 kW; 2,760 to 3,160 shp) for use while surfaced, two AEG GU 460/8-276 double-acting electric motors producing a total of 750 metric horsepower (550 kW; 740 shp) for use while submerged.

[4] On 10 May 1945, U-1272 surrendered at Bergen, Norway, after only one war patrol, which resulted in no ship damaged or sunk.

Of the 156 U-boats that eventually surrendered to the Allied forces at the end of the war, U-1272 was one of 116 selected to take part in Operation Deadlight.