She was a founder of the Child protection society of Western Australia as well as an early advocate for homes for the aged and daycare centres.

[2] However, she and her two fellow female medical students, Violet Plummer and Christina L. Goode, had to defend themselves against claims of impropriety - in particular, Mead wrote in letters to the newspapers, that they had "on no occasion examined any patient after 5 p.m."[2] Their cohort eventually transferred to the University of Melbourne, graduating in 1897.

She became a medical adviser to the Ministering Children's League Convalescent Home and a nurse edicator of the St John Ambulance Association.

[2] Mead and Roberta Jull initiated the West Australian Health Society to address "the alarming mortality among infants", making suggestions for the education of mothers and improvement of sanitation in dairies to the Colonial Secretary of Western Australia.

[2] Mead was a medical officer for the House of Mercy for unmarried mothers from 1904 to 1907, and physician for the Perth Children's Hospital which opened in 1909.

[7] She also represented that association on the Western Australian Council for Venereal Disease and presented a report in 1918 calling for greater education of nurses on the subject.

[1] During World War I, Mead taught Red Cross nurses and was a medical officer at the Fremantle Base Hospital as well as a Perth divisional surgeon.

"[11] In 1912, Mead joined the committee of the Silver Chain Nursing League and proposed a scheme to build cottage homes for elderly people.