Melike İsmetüddin Gevher Nesibe was an early 13th century princess of the Sultanate of Rum, the daughter of Kilij Arslan II and sister of Kaykhusraw I.
According to legend, Gevher Nesibe fell in love with a cavalry officer defending the palace of the Seljuk sultan at Konya.
Her brother Kaykhusraw I opposed marriage between his sister and the officer so he sent the young man on a various dangerous assignments and campaigns to ensure his death.
The entryway inscription, a common feature of Islamic architecture that usually records the architect's name, is missing, but the information is preserved in written sources elsewhere.
The Seljuk hospitals in Anatolia, on one hand being a health facility, were also places where physicians were educated through a master-apprentice relationship.