The Ghaghra Khan Bari Jame Mosque (Bengali: ঘাঘড়া খাঁন বাড়ী মসজিদ, Arabic: المسجد غغرا خان باري) is a medieval-era mosque located in the Khan Bari of the Ghaghra Laskar village in Hatibandha Union, Jhenaigati Upazila, Sherpur District, in the Mymensingh Division of northern Bangladesh.

It is an example of Mughal architecture, and since 1999, its preservation has been entrusted to the country's Bangladeshi Department of Archaeology.

A rock inscription at the door contains Arabic writing which states that the mosque was built in AH 1028 (1618/1619 CE).

The walls, made of gathuni lime and brick-dust, are 1.2 metres (4 ft).

Of the total land area, 58% comprises the mosque, which is under the waqf by locals.