"Ghetto Cowboy" is the lead single by American hip hop collective Mo Thugs taken from their second studio album Chapter II: Family Reunion, released in 1998 via Mo Thugs/Relativity Records.

Produced by Krayzie Bone with co-production by Romeo Antonio.

The single peaked at 15 on the Billboard Hot 100 while also reaching the top spot on the Hot Rap Singles chart.

It was certified gold by the Recording Industry Association of America on December 17, 1998 for sales of 500,000 copies and also made it to No.

^ Shipments figures based on certification alone.