The album was released as a double disc set, featuring a large selection of guest appearances, including Bone Thugs-n-Harmony, Mo Thugs, Mariah Carey, ThugLine, The Marley Brothers, Big Pun, Fat Joe, Cuban Link, Gangsta Boo, E-40, 8 Ball & MJG, Kurupt, Naughty By Nature and Snoop Dogg.

In 2001, Krayzie Bone released Thug On Da Line, which received generally positive reviews from music critics and went gold.

During an April 2014 press conference, Krayzie Bone announced that the first installment of the Chasing the Devil trilogy album would be released July 22, 2014 by RBC Records.

As a part of his entrepreneurial drive, Krayzie Bone launched a clothing and accessory line named "TL Apparel"[5] which is a direct tie to his music.

With his name back in the spotlight, Krayzie Bone has seized this opportunity to start the "Spread the Love" foundation, a venture in which investments are used to help the youth excel in music and arts within the Cleveland community.

On the music side of things, Krayzie Bone teamed up with Fatlip (of The Pharcyde) to assist on the lead single, "Dust in the Wind," from the album Sccit & Siavash The Grouch Present… Torpor.

[9] On September 24, 2023, Krayzie Bone was admitted to a hospital in Los Angeles after coughing up blood in his sleep, what was later attributed to sarcoidosis.