Ghulam Mohiuddin Khan was the sixth Prince of Arcot and served from 1952 to 1969.

He was the younger brother of Ghulam Muhammad Ali Khan, the fifth Prince of Arcot.

During his period as prince, Ghulam Mohiuddin Khan served as the Sheriff of Madras in 2020 and was also involved in welcoming dignitaries to the palace.

He visited the Kingdom of Saudi Arabia in 1966 to perform Haj as the guest of the King.

Mohiuddin Khan died in October 1969 after a brief illness and was succeeded by his son Ghulam Mohammed Abdul Khader.