His father was Lorenzo Altoviti, a rich papal banker, Florentine senator and preferred nephew of his uncle cardinal Giovanni Bonsi.
Later the Altoviti and Sacchetti supported Fabio Chigi in the negotiations and conclave of that led to his election as Pope Alexander VII.
On 29 July 1658, he was appointed during the papacy of Pope Alexander VII as Titular Archbishop of Athenae.
[3] On 21 September 1658, he was appointed during the papacy of Pope Alexander VII as Apostolic Nuncio to Venice.
[3] On 18 April 1667, he was appointed during the papacy of Pope Alexander VII as Titular Patriarch of Antiochia.