G. Rozza was born and raised in Italy where he earned a bachelor's and master's degree in Aerospace Engineering from the Polytechnic University of Milan in the year 2002.

His thesis, titled 'Shape Design by Optimal Flow Control and Reduced basis Techniques: Applications to Bypass Configurations in Haemodynamics', was completed under the supervision of Alfio Quarteroni and Anthony Tyr Patera.

[2] Following his doctoral studies, G. Rozza worked at Ecole Polytechnique Fédérale de Lausanne in the professor Alfio Quarteroni's scientific group for a year.

[10] In September 2022 he was listed in the World's Top 2% Scientist ranking, made by Stanford University in collaboration with Elsevier and Scopus.

[12][13] In addition to research, G. Rozza is the President of SMACT Innovation Ecosystem's supervisory board, and he is an executive committee member of ECCOMAS (European Community on Computational Methods in Applied Sciences).