[1] She has appeared in roles in the feature films Star Trek Into Darkness (2013), Mother's Day (2016), I Can Only Imagine (2018), Unbroken: Path to Redemption (2018), and several television series.

[4][5] Around the time Simone entered the foster care system, she enrolled at a gym, where she met the owner Kathy DeMarco, who became her mentor.

[2][4] She signed her first modeling contract with Boston's Maggie Inc. in 2009, and appeared in advertisements for the American Dental Association, Carolina Herrera, Elie Saab, Hasbro, New Balance, Reebok, and Vera Wang.

She began to focus on acting when she enrolled at Bunker Hill Community College and then joined the Screen Actors Guild shortly after.

[8][better source needed] Simone has also appeared in several television series, including Law & Order: Criminal Intent, Chuck, and Hitting the Breaks,[4][5] which she co-produced with Pure Flix Entertainment through her company GS Productions.