Gianni Francesco Mattioli (born 29 January 1940 in Genoa) is an Italian politician and university professor.

Mattioli graduated with a def in physics in 1964 with a thesis on the diffusion of high energy particles.

In 1996, he was appointed undersecretary of public works in the first Prodi government; in those years, he joined the executive committee of Legambiente.

From 2000 to 2001, he also served as Minister of Community Policies in the Amato II Cabinet, after his party colleague, Edo Ronchi, refused this post.

On 20 December 2009, Mattioli joined the national coordination of Left Ecology Freedom, of which he later became responsible for environmental policies.