[1] Starting from the late 1950s, Musy began an intense activity as a character actor, often being cast in villainous roles.

[1] Musy became best known through his television work, notably the RAI TV series La freccia nera, Le inchieste del commissario Maigret, E le stelle stanno a guardare and Dov'è Anna?.

[1][2] Also remembered for playing distinctive characters in some of his film work,[2] in 1993 Musy portrayed Sicilian mafioso Tommaso Buscetta in Giuseppe Ferrara's film Giovanni Falcone; despite panning the end result, critics still praised the actors.

In his animated roles, Musy voiced Giuseppe Garibaldi in the Italian film L'eroe dei due mondi, directed by Guido Manuli in 1994 and served as the Italian voice of Zeus in Hercules and Billy Bones in Treasure Planet.

[4] Musy died before being able to post-syncronize his own dialogue for his final film role, so in The Day of the Siege: September Eleven 1683 Sergio Graziani's voice is heard instead of his.