In 1971, he co-founded the Chagoury Group with his younger brother Ronald Chagoury,[3][4] an industrial conglomerate with interests in construction, real estate and property development, flour mills, water bottling and purification, glass manufacturing, insurance, hotels, furniture manufacturing, telecommunications, IT, catering and international financing.
[10] Chagoury was a close associate of Nigerian dictator, General Sani Abacha, who helped his business interests in the country.
After Abacha died in 1998, Chagoury returned an estimated $300 million to the Nigerian government to secure his indemnity from possible criminal charges.
[2][11] In 2010, the U.S. Department of Homeland Security apologized to Chagoury after detaining him at Teterboro Airport for over four hours because of inclusion on a no-fly list.
[14] He is a key benefactor for St. Jude Children's Research Hospital in Memphis, Tennessee, and his private contributions have improved health care and public infrastructure of Miziara, Northern Lebanon, home to both his and his wife's family.