Giles Corner (formerly Giles' Corner) (Postcode 5411) is the name of the intersection of Main North Road (now called Horrocks Highway) and the Barrier Highway, halfway between the towns of Tarlee and Rhynie.

Horrocks Highway continues in a northerly direction, on to the towns of Rhynie, Auburn and Clare.

Although not a town, Giles Corner is sign posted to mark its location.

Thomas Giles was a business partner of George Alexander Anstey, who was an early pastoralist on the Yorke Peninsula and is remembered by the landmark Anstey Hill Recreation Park in the Adelaide Hills, overlooking the Adelaide suburb of Hope Valley.

Owing to vandalism the buildings were later demolished and now a house stands on the site.