Kvirikashvili has led initiatives to advance Euro-Atlantic and European integration and highlight Georgia as an attractive location for foreign investment.

In the same year, kvirikashvili joined president Eduard Shevardnadze's Ruling Party, Union of Citizens of Georgia (UCG) and became member of parliament.

[4][6] In December 2015, Kviriashvili was nominated by the Georgian Dream coalition as new prime minister after Irakli Garibashvili announced his resignation.

"[10] In May 2018, two waves of protests erupted in Tbilisi: one over police raids on nightclubs over alleged illegal drug trade, and another over perceived miscarriage of justice by the Prosecutor's Office of Georgia in the case involving killing of teenagers in a street knife-combat.

[11] On 1 June 2018, Prime Minister Irakli Kvirikashvili announced that the case would be transferred from the Prosecutor's Office to the Ministry of Internal Affairs for further investigation, and the creation of a special parliamentary fact-finding commission chaired by an opposition politician.

[13] The Minister of Internal Affairs Giorgi Gakharia showed up in front of protesters on May 13 and apologized for alleged instances of police misconduct.