He was formed in Genoa with Giovanni Andrea de Ferrari and Domenico Fiasella according to the information provided by the contemporary Genoese biographer Raffaele Soprani.
[2] His presence is documented from in 1634 in Rome where he made drawings after the statues and ancient reliefs at the famous Giustiniani collection.
In Rome his art evolved in contact with the works of Poussin, Andrea di Leone, Pietro Testa and the Flemish artists François Duquesnoy and Karel Philips Spierincks.
He dedicated a series of prints to the pleasures of wine to Paolo Giordano Orsini II, Prince of Bracciano.
[1] A Worship of Venus etched after Titian was dedicated to Cassiano dal Pozzo and other prints of bacchanals to Fabio della Cornia.
[1][2] The few drawings by Podesta that have been preserved show features familiar from his etchings: contorted facial expressions, small twisting figures, patches of dark cross-hatching and an interest in still-life.