Giovanni Battista Innocenzo Colombo (16 December 1717 – 10 April 1801) was a Swiss painter and stage set designer.

For 18 years, he was the court architect at Stuttgart and stage set designer for the Duke.

In Stuttgart, he created the set designs for operas of Niccolò Jommelli, and the ballets of Jean-Georges Noverre.

From 1769 to 1771, he was the stage set designer for the Teatro Regio, substituting for the members of the Galliari family.

An example of work in that theatre is his sets for the 1770 opera Annibale a Torino, written by Jacopo Durandi, with music by Giovanni Paisiello.